Biomaterial Database

Sodium metabolism during acclimation to water restriction by wild mice, Mus musculus. 1981

T M McKenna, and H Haines

Changes in sodium and potassium balance and urinary aldosterone excretion (free plus "acid labile") were surveyed in house mice acclimating initially to 1/2 the ad libitum water ration and later to 1/4 of ad libitum. Each water restriction caused negative sodium and potassium balance, followed by conservation of both ions. At the first water restriction, negative balance was produced by natriuresis and kaliuresis, at successive water restriction, a negative balance was due to a decrease in food consumption. Aldosterone excretion doubled at the 1/2 ad libitum restriction, and then generally remained at control levels thereafter. Fractional intestinal absorption of both ions showed a persistent increase after the 3rd day of water restriction. The Na:K ratio in urine and feces declined as mice responded to each water restriction and returned to control levels in acclimated animals.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009318	Natriuresis	Sodium excretion by URINATION.	Natriureses
D011188	Potassium	An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
D005260	Female		Females
D000064	Acclimatization	Adaptation to a new environment or to a change in the old.	Acclimation
D000450	Aldosterone	A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.	Aldosterone, (+-)-Isomer,Aldosterone, (11 beta,17 alpha)-Isomer
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012964	Sodium	A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.	Sodium Ion Level,Sodium-23,Ion Level, Sodium,Level, Sodium Ion,Sodium 23
D014868	Water Deprivation	The withholding of water in a structured experimental situation.	Deprivation, Water,Deprivations, Water,Water Deprivations
D014882	Water-Electrolyte Balance	The balance of fluid in the BODY FLUID COMPARTMENTS; total BODY WATER; BLOOD VOLUME; EXTRACELLULAR SPACE; INTRACELLULAR SPACE, maintained by processes in the body that regulate the intake and excretion of WATER and ELECTROLYTES, particularly SODIUM and POTASSIUM.	Fluid Balance,Electrolyte Balance,Balance, Electrolyte,Balance, Fluid,Balance, Water-Electrolyte,Water Electrolyte Balance