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Serum prealbumin concentrations have been studied, by a quantitative immunological procedure, in patients with secondary carcinoma of the liver, chronic active hepatitis, alcoholic hepatitis, cryptogenic cirrhosis, obstructive jaundice, inflammatory bowel disease, and myocardial infarction. The results showed that prealbumin concentration is significantly decreased when liver function is impaired. In diseases not associated with liver damage the concentrations of prealbumin were within the normal range. The advantage of this biochemical procedure is that serum prealbumin concentration is a true index of liver function, whereas serum enzyme activities signify only the degree of hepatocellular damage, which may not always quantitatively reflect liver function. Determination of serum prealbumin is therefore valuable in the diagnosis of liver disease and in the monitoring of treatment.
D R Hutchinson, and
R P Halliwell, and
M G Smith, and
D V Parke
July 1980,
Lancet (London, England),
D R Hutchinson, and
R P Halliwell, and
M G Smith, and
D V Parke
August 1974,
Postgraduate medicine,
D R Hutchinson, and
R P Halliwell, and
M G Smith, and
D V Parke
March 1994,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
D R Hutchinson, and
R P Halliwell, and
M G Smith, and
D V Parke
January 1956,
Biochemische Zeitschrift,
D R Hutchinson, and
R P Halliwell, and
M G Smith, and
D V Parke
August 1995,
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D R Hutchinson, and
R P Halliwell, and
M G Smith, and
D V Parke
January 1959,
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D R Hutchinson, and
R P Halliwell, and
M G Smith, and
D V Parke
February 1969,
Obstetrics and gynecology,
D R Hutchinson, and
R P Halliwell, and
M G Smith, and
D V Parke
November 1965,
Scottish medical journal,
D R Hutchinson, and
R P Halliwell, and
M G Smith, and
D V Parke
July 1987,
Clinical chemistry,
D R Hutchinson, and
R P Halliwell, and
M G Smith, and
D V Parke
January 1987,
Preparative biochemistry,
