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Arachidonic acid is converted by washed platelets from man, horse and dog into a mixture of 8,9,12-trihydroxyeicosa-5,10,14-trienoic acid and 8,11,12-trihydroxyeicosa-5,9,14-trienoic acid (termed 8,9,12-THETA and 8,11,12-THETA respectively and THETA collectively). Gas chromatographic--mass spectrometric evidence of structure is discussed.
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