Biomaterial Database

[Clinical anatomical study of a case of amnesic encephalitis of herpetic origin (author's transl)]. 1978

J Barbizet, and P Duizabo, and J Poirier

A report on a case of herpes encephalitis in a patient of particularly high intellectual level who was kept under observation for a period of 13 years. Anatomical examination of the brain demonstrated massive bilateral destruction of the limbic system. Having studied the higher functions of this patient for many months it was possible to establish interesting correlations relating to the role of the limbic system. It appears to be indispensable for the utilization of verbal, praxognosic, and conceptual information. Though this is still retained in the intact neocortex, mobilization of the information is possible only when stimuli arise from the exterior and for as long as they last. Spontaneous evocation of this data is, in fact, impossible, as is the stocking of new information. The limbic system, therefore, while not being the site of retention of memorised informations which is the role of the neocortex, appears to be a logic system. Which is indispensable for proper functioning of the memory machine.

UI	MeSH Term	Description	Entries
D008032	Limbic System	A set of forebrain structures common to all mammals that is defined functionally and anatomically. It is implicated in the higher integration of visceral, olfactory, and somatic information as well as homeostatic responses including fundamental survival behaviors (feeding, mating, emotion). For most authors, it includes the AMYGDALA; EPITHALAMUS; GYRUS CINGULI; hippocampal formation (see HIPPOCAMPUS); HYPOTHALAMUS; PARAHIPPOCAMPAL GYRUS; SEPTAL NUCLEI; anterior nuclear group of thalamus, and portions of the basal ganglia. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p744; NeuroNames, http://rprcsgi.rprc.washington.edu/neuronames/index.html (September 2, 1998)).	Limbic Systems,System, Limbic,Systems, Limbic
D008297	Male		Males
D008568	Memory	Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
D009336	Necrosis	The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D003210	Concept Formation	A cognitive process involving the formation of ideas generalized from the knowledge of qualities, aspects, and relations of objects.	Concept Acquisition,Concept Learning,Conceptualization,Acquisition, Concept,Acquisitions, Concept,Concept Acquisitions,Formation, Concept,Learning, Concept
D004660	Encephalitis	Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.	Inflammation, Brain,Rasmussen Syndrome,Brain Inflammation,Encephalitis, Rasmussen,Rasmussen Encephalitis,Rasmussen's Syndrome,Brain Inflammations
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006561	Herpes Simplex	A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)	Herpes Simplex Virus Infection
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults