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The heterogeneity of the specificities of anti-acetylcholine receptor (anti-AChR) antibodies of myasthenia gravis (MG) patients has been demonstrated by comparing reactions against a panel of xenogeneic AChR. For each patient there was a more or less unique cross-reactivity profile. Such heterogeneity emphasizes the need to use human AChR for the routine detection of anti-AChR. In vitro cross-reactivity was important in predicting the effect of anti-AChR after passive transfer to rats. Specificity may influence the outcome in human neonates receiving maternal anti-AChR via the placenta. In contrast to the extreme heterogeneity seen in spontaneous MG, the antibodies associated with D-penicillamine-induced MG were more homogeneous.
M J Garlepp, and
P H Kay, and
R L Dawkins, and
R C Bucknall, and
A Kemp
September 1991,
Journal of the neurological sciences,
M J Garlepp, and
P H Kay, and
R L Dawkins, and
R C Bucknall, and
A Kemp
January 1982,
Journal of immunology (Baltimore, Md. : 1950),
M J Garlepp, and
P H Kay, and
R L Dawkins, and
R C Bucknall, and
A Kemp
March 2000,
Clinical and experimental immunology,
M J Garlepp, and
P H Kay, and
R L Dawkins, and
R C Bucknall, and
A Kemp
January 2002,
Lupus,
M J Garlepp, and
P H Kay, and
R L Dawkins, and
R C Bucknall, and
A Kemp
June 2008,
Journal of neuroimmunology,
M J Garlepp, and
P H Kay, and
R L Dawkins, and
R C Bucknall, and
A Kemp
November 2010,
Clinical neurology and neurosurgery,
M J Garlepp, and
P H Kay, and
R L Dawkins, and
R C Bucknall, and
A Kemp
May 1991,
Journal of clinical immunology,
M J Garlepp, and
P H Kay, and
R L Dawkins, and
R C Bucknall, and
A Kemp
June 2000,
Journal of neuroimmunology,
M J Garlepp, and
P H Kay, and
R L Dawkins, and
R C Bucknall, and
A Kemp
March 1993,
Neurology,
M J Garlepp, and
P H Kay, and
R L Dawkins, and
R C Bucknall, and
A Kemp
January 1987,
Monographs in allergy,
