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[Effects of concanavalin A on neural induction in the young gastrula of the axolotl (Ambystoma mexicanum Shaw. ) and pleurodele (Pleurodeles waltlii Michah.)]. 1981

M Sadoughi

Presumptive ectoderm from young gastrulae of the Pleurodele and the Axolotl was treated with concanavalin A(5-25 micrograms/ml). Then, it was combined, in a sandwich, with the dorsal lip of the blastopore and cultured in vitro for 5-7 days. The results of the experiments show that the treated ectoderm becomes more fragile than untreated control ectoderm. Nevertheless, the neural induction and the histological differentiation of the neural tissue appeared in a rather normal fashion.

UI MeSH Term Description Entries
D009420 Nervous System The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed) Nervous Systems,System, Nervous,Systems, Nervous
D010999 Pleurodeles A genus of aquatic newts belonging to the family Salamandridae and sometimes referred to as "spiny" tritons. There are two species P. waltlii and P. poireti. P. waltlii is commonly used in the laboratory. Since this genus adapts to aquarium living, it is easy to maintain in laboratories. Pleurodele
D002454 Cell Differentiation Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs. Differentiation, Cell,Cell Differentiations,Differentiations, Cell
D003208 Concanavalin A A MANNOSE/GLUCOSE binding lectin isolated from the jack bean (Canavalia ensiformis). It is a potent mitogen used to stimulate cell proliferation in lymphocytes, primarily T-lymphocyte, cultures.
D004475 Ectoderm The outer of the three germ layers of an embryo. Apical Ectodermal Ridge,Apical Ectodermal Ridges,Ectodermal Ridge, Apical,Ectoderms
D004627 Embryonic Induction The complex processes of initiating CELL DIFFERENTIATION in the embryo. The precise regulation by cell interactions leads to diversity of cell types and specific pattern of organization (EMBRYOGENESIS). Embryonic Inductions,Induction, Embryonic,Inductions, Embryonic
D005775 Gastrula The developmental stage that follows BLASTULA or BLASTOCYST. It is characterized by the morphogenetic cell movements including invagination, ingression, and involution. Gastrulation begins with the formation of the PRIMITIVE STREAK, and ends with the formation of three GERM LAYERS, the body plan of the mature organism. Archenteron,Blastopore,Gastrocoele,Primitive Gut,Archenterons,Blastopores,Gastrocoeles,Gastrulas,Gut, Primitive,Guts, Primitive,Primitive Guts
D000558 Ambystoma mexicanum A salamander found in Mexican mountain lakes and accounting for about 30 percent of the urodeles used in research. The axolotl remains in larval form throughout its life, a phenomenon known as neoteny. Axolotl,Mexican Salamander,Ambystoma mexicanums,Axolotls,Salamander, Mexican,mexicanums, Ambystoma
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

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