Biomaterial Database

Allergens in hymenoptera venom. VII. Species specific reactivity to yellow jacket venoms. 1981

D R Hoffman, and C A McDonald

Venom from three species of yellow jacket, Vespula maculifrons, V. squamosa and Vespa crabro, was tested in direct and inhibition of RAST with a panel of 39 sera from three regions of the U.S. V. squamosa venom was found to be missing at least one allergen present in V. maculifrons. Patterns of reactivity were highly correlated with geography; reactivity with V. squamosa correlated with distribution of the species. Sera fron California recognized Vespa crabro; however, the insect is not found west of Indiana. This suggests that there are also some differences in the venom from the western species, V. pennsylvanica. No correlations were found with reactivity to hornet, wasp or bee venoms.

UI	MeSH Term	Description	Entries
D011852	Radioallergosorbent Test	An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.	Radioimmunosorbent Assay of Allergens,Allergens Radioimmunosorbent Assay,Allergens Radioimmunosorbent Assays,Radioallergosorbent Tests,Test, Radioallergosorbent,Tests, Radioallergosorbent
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006927	Hymenoptera	An extensive order of highly specialized insects including bees, wasps, and ants.
D000485	Allergens	Antigen-type substances that produce immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).	Allergen
D001514	Bee Venoms	Toxins obtained from Apis mellifera (honey bee) and related species. They contain various enzymes, polypeptide toxins, and other substances, some of which are allergenic or immunogenic or both. These venoms were formerly used in rheumatism to stimulate the pituitary-adrenal system.	Apis Venoms,Honeybee Venom,Honeybee Venoms,Apitoxin,Bee Venom,Venom, Bee,Venom, Honeybee,Venoms, Apis,Venoms, Bee,Venoms, Honeybee
D001665	Binding Sites	The parts of a macromolecule that directly participate in its specific combination with another molecule.	Combining Site,Binding Site,Combining Sites,Site, Binding,Site, Combining,Sites, Binding,Sites, Combining
D013045	Species Specificity	The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.	Species Specificities,Specificities, Species,Specificity, Species
D014862	Wasp Venoms	Venoms produced by the wasp (Vespid) family of stinging insects, including hornets; the venoms contain enzymes, biogenic amines, histamine releasing factors, kinins, toxic polypeptides, etc., and are similar to bee venoms.	Vespid Venoms,Vespa Venoms,Vespid Venom,Wasp Venom,Venom, Vespid,Venom, Wasp,Venoms, Vespa,Venoms, Vespid,Venoms, Wasp