Disposition of radiolabeled benzoquinolizinyl propionanilide hydrochloride in rats and dogs and identification of several of its metabolites. 1978

J L Leeling, and I A Muni, and T L Kowalski, and N Johnson

UI MeSH Term Description Entries
D007408 Intestinal Absorption Uptake of substances through the lining of the INTESTINES. Absorption, Intestinal
D008297 Male Males
D011807 Quinolizines
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D005260 Female Females
D006207 Half-Life The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity. Halflife,Half Life,Half-Lifes,Halflifes
D000813 Anilides Any aromatic amide obtained by acylation of aniline.
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000959 Antihypertensive Agents Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. Anti-Hypertensive,Anti-Hypertensive Agent,Anti-Hypertensive Drug,Antihypertensive,Antihypertensive Agent,Antihypertensive Drug,Anti-Hypertensive Agents,Anti-Hypertensive Drugs,Anti-Hypertensives,Antihypertensive Drugs,Antihypertensives,Agent, Anti-Hypertensive,Agent, Antihypertensive,Agents, Anti-Hypertensive,Agents, Antihypertensive,Anti Hypertensive,Anti Hypertensive Agent,Anti Hypertensive Agents,Anti Hypertensive Drug,Anti Hypertensive Drugs,Anti Hypertensives,Drug, Anti-Hypertensive,Drug, Antihypertensive,Drugs, Anti-Hypertensive,Drugs, Antihypertensive
D014018 Tissue Distribution Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios. Distribution, Tissue,Distributions, Tissue,Tissue Distributions

Related Publications

J L Leeling, and I A Muni, and T L Kowalski, and N Johnson
November 1988, Arzneimittel-Forschung,
J L Leeling, and I A Muni, and T L Kowalski, and N Johnson
January 2002, Biopharmaceutics & drug disposition,
J L Leeling, and I A Muni, and T L Kowalski, and N Johnson
August 2000, Drug metabolism and disposition: the biological fate of chemicals,
J L Leeling, and I A Muni, and T L Kowalski, and N Johnson
April 1988, Journal of pharmacobio-dynamics,
J L Leeling, and I A Muni, and T L Kowalski, and N Johnson
July 1995, Arzneimittel-Forschung,
J L Leeling, and I A Muni, and T L Kowalski, and N Johnson
December 2000, Regulatory toxicology and pharmacology : RTP,
J L Leeling, and I A Muni, and T L Kowalski, and N Johnson
June 2018, Xenobiotica; the fate of foreign compounds in biological systems,
J L Leeling, and I A Muni, and T L Kowalski, and N Johnson
January 1984, Drug metabolism and disposition: the biological fate of chemicals,
J L Leeling, and I A Muni, and T L Kowalski, and N Johnson
July 1970, The Journal of pharmacology and experimental therapeutics,
J L Leeling, and I A Muni, and T L Kowalski, and N Johnson
May 2024, Current drug metabolism,
Copied contents to your clipboard!