-transparent.png){kind=logo}
Fibroblasts were cultured from skin biopsies of patients with systemic sclerosis in different stages of the disease. In vitro synthesis of collagen was checked after a pulse with tritiated proline. The ratio between type I and type III collagen was normal in all patients. Six of seven cultures derived from patients in the active state showed an increased synthesis of collagen relative to other proteins. Addition of serum (normal and diseased) to the culture medium did not stimulate synthesis of collagen in any culture with normal collagen synthesis.
Related Publications
T Krieg, and
C Luderschmidt, and
L Weber, and
P K Müller, and
O Braun-Falco
January 1985,
Annals of the New York Academy of Sciences,
T Krieg, and
C Luderschmidt, and
L Weber, and
P K Müller, and
O Braun-Falco
January 1976,
Arthritis and rheumatism,
T Krieg, and
C Luderschmidt, and
L Weber, and
P K Müller, and
O Braun-Falco
April 1977,
Arthritis and rheumatism,
T Krieg, and
C Luderschmidt, and
L Weber, and
P K Müller, and
O Braun-Falco
January 1977,
Arthritis and rheumatism,
T Krieg, and
C Luderschmidt, and
L Weber, and
P K Müller, and
O Braun-Falco
January 1981,
Molecular and cellular biochemistry,
T Krieg, and
C Luderschmidt, and
L Weber, and
P K Müller, and
O Braun-Falco
October 1974,
The Journal of clinical investigation,
T Krieg, and
C Luderschmidt, and
L Weber, and
P K Müller, and
O Braun-Falco
May 1981,
The Journal of investigative dermatology,
T Krieg, and
C Luderschmidt, and
L Weber, and
P K Müller, and
O Braun-Falco
January 1991,
Cellular and molecular biology,
T Krieg, and
C Luderschmidt, and
L Weber, and
P K Müller, and
O Braun-Falco
June 1985,
Arthritis and rheumatism,
T Krieg, and
C Luderschmidt, and
L Weber, and
P K Müller, and
O Braun-Falco
January 1986,
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
