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The percentage of brain or liver chromatin in the template-active region was examined in rats of varying ages. Prenatally, there was an increase in the percentage of brain template-active region chromatin which declined near birth. After birth, the percentage of brain template-active region chromatin again increased to 3-6 days of age and then declined to adult levels at about 15 days of age. Liver exhibited a similar gestational change in the percentage of template-active region chromatin, but there was no recovery from the birth decline during postnatal development. These findings are discussed in terms of their contribution to the understanding of age-dependent changes in brain transcription.
L Uphouse, and
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L Uphouse, and
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L Uphouse, and
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L Uphouse, and
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