Biomaterial Database

Anthelmintic activity of albendazole against Filaroides hirthi lungworms in dogs. 1978

J R Georgi, and D O Slauson, and V J Theodorides

Albendazole given at a dosage rate of 25 to 50 mg/kg twice daily for 5 days killed all but a small proportion and sterilized the few surviving Filaroides hirthi worms in artificially infected Beagle pups. Extensive tissue reaction around the dead worms persisted for an undetermined length of time. However, albendazole treatment of mature stock should prove useful in preventing transmission of F hirthi infection to their offspring and thus provide an efficient means of control.

UI	MeSH Term	Description	Entries
D008168	Lung	Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.	Lungs
D008174	Lung Diseases, Parasitic	Infections of the lungs with parasites, most commonly by parasitic worms (HELMINTHS).	Parasitic Lung Diseases,Parasitic Infections of Lung,Pulmonary Parasitic Infections,Lung Disease, Parasitic,Lung Parasitic Infection,Lung Parasitic Infections,Parasitic Infection, Pulmonary,Parasitic Infections, Pulmonary,Parasitic Lung Disease,Pulmonary Parasitic Infection
D008681	Metastrongyloidea	A superfamily of nematodes of the order STRONGYLIDA. Characteristics include a fluid-filled outer layer of cuticle and a reduced mouth and bursa.	Metastrongyloideas
D009349	Nematode Infections	Infections by nematodes, general or unspecified.	Infections, Nematode,Infection, Nematode,Nematode Infection
D004283	Dog Diseases	Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.	Canine Diseases,Canine Disease,Disease, Canine,Disease, Dog,Diseases, Canine,Diseases, Dog,Dog Disease
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000871	Anthelmintics	Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.	Anthelmintic,Antihelmintic,Vermifuge,Vermifuges,Antihelmintics
D001562	Benzimidazoles	Compounds with a BENZENE fused to IMIDAZOLES.