Biomaterial Database

Efficacy of droncit against Echinococcus granulosus infection in dogs. 1978

A S Thakur, and U Prezioso, and N Marchevsky

A study was made on 120 dogs to evaluate the effectiveness of droncit against Echinococcus granulous infection. The drug was administered orally in tablet form at dose rates of 1.25, 2.5, 5.0,and 10.0 mg/kg of body weight against immature stages of the parasite and at a dose rate of 5.0 mg/kg against gravid worms. Droncit was found to be 100% effective against both immature and gravid worms at the dose rate of 5.0 mg/kg. Adverse reactions were not observed in the treated dogs, and no risk was involved in administering the drug. The use of droncit in hydatidosis control programs in discussed.

UI	MeSH Term	Description	Entries
D007546	Isoquinolines	A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
D008297	Male		Males
D011719	Pyrazines	A heterocyclic aromatic organic compound with the chemical formula C4H4N2.	Pyrazine
D004283	Dog Diseases	Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.	Canine Diseases,Canine Disease,Disease, Canine,Disease, Dog,Diseases, Canine,Diseases, Dog,Dog Disease
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D004443	Echinococcosis	An infection caused by the infestation of the larval form of tapeworms of the genus Echinococcus. The liver, lungs, and kidney are the most common areas of infestation.	Cystic Echinococcosis,Cysts, Hydatid,Hydatid Cyst,Hydatidosis,Echinococcus Granulosus Infection,Echinococcus Infection,Hydatid Disease,Cyst, Hydatid,Cystic Echinococcoses,Echinococcoses,Echinococcoses, Cystic,Echinococcosis, Cystic,Echinococcus Granulosus Infections,Echinococcus Infections,Granulosus Infection, Echinococcus,Granulosus Infections, Echinococcus,Hydatid Cysts,Hydatid Diseases,Hydatidoses,Infection, Echinococcus,Infection, Echinococcus Granulosus,Infections, Echinococcus Granulosus
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000980	Antiplatyhelmintic Agents	Agents used to treat cestode, trematode, or other flatworm infestations in man or animals.	Antiplatyhelmintic Drugs,Antiplatyhelmintics,Agents, Antiplatyhelmintic,Drugs, Antiplatyhelmintic