Reassessment of the management of benign gastric ulcer with achlorhydria. 1981

M R Sogge, and M L Butler

Previous reports of benign gastric ulcer with achlorhydria have recommended surgical removal of the ulcer, even though a malignant process had not been demonstrated. We report a patient with achlorhydria and a gastric ulcer who, at exploration 4 weeks after discovery, had only a healed ulcer. Its benign nature was demonstrated by endoscopic biopsies and cytology and confirmed at surgery. The patient has remained achlorhydric on follow-up and has not had further ulcers. We recommend that, after multiple endoscopic biopsies and cytology have adequately excluded a malignant process, a gastric ulcer be followed to complete healing, even in the presence of achlorhydria. If healing is incomplete by 6-12 weeks, surgical intervention should be contemplated, just as for more routine gastric ulcers.

UI MeSH Term Description Entries
D008297 Male Males
D005744 Gastric Acid Hydrochloric acid present in GASTRIC JUICE. Hydrochloric Acid, Gastric,Acids, Gastric,Acids, Gastric Hydrochloric,Gastric Acids,Gastric Hydrochloric Acid,Gastric Hydrochloric Acids,Hydrochloric Acids, Gastric
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000126 Achlorhydria A lack of HYDROCHLORIC ACID in GASTRIC JUICE despite stimulation of gastric secretion. Achylia Gastrica,Hypochlorhydria
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D013276 Stomach Ulcer Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS). Gastric Ulcer,Gastric Ulcers,Stomach Ulcers,Ulcer, Gastric,Ulcer, Stomach,Ulcers, Gastric,Ulcers, Stomach

Related Publications

M R Sogge, and M L Butler
March 1951, Gastroenterology,
M R Sogge, and M L Butler
October 1979, Acta hepato-gastroenterologica,
M R Sogge, and M L Butler
November 1964, Bulletin of gastrointestinal endoscopy,
M R Sogge, and M L Butler
February 1978, Archives of surgery (Chicago, Ill. : 1960),
M R Sogge, and M L Butler
December 1951, British medical journal,
M R Sogge, and M L Butler
February 1953, The Review of gastroenterology,
M R Sogge, and M L Butler
September 1949, Gastroenterology,
M R Sogge, and M L Butler
January 1983, International surgery,
M R Sogge, and M L Butler
November 1953, The South Dakota journal of medicine and pharmacy,
Copied contents to your clipboard!