BIOMAT Database Logo BIOMAT Database Logo

Normal cortical concentration of cholecystokinin-like immunoreactivity with reduced choline acetyltransferase activity in senile dementia of Alzheimer type. 1981

M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen

UI MeSH Term Description Entries
D008297 Male Males
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D002421 Caudate Nucleus Elongated gray mass of the neostriatum located adjacent to the lateral ventricle of the brain. Caudatus,Nucleus Caudatus,Caudatus, Nucleus,Nucleus, Caudate
D002540 Cerebral Cortex The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulci. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions. Allocortex,Archipallium,Cortex Cerebri,Cortical Plate,Paleocortex,Periallocortex,Allocortices,Archipalliums,Cerebral Cortices,Cortex Cerebrus,Cortex, Cerebral,Cortical Plates,Paleocortices,Periallocortices,Plate, Cortical
D002766 Cholecystokinin A peptide, of about 33 amino acids, secreted by the upper INTESTINAL MUCOSA and also found in the central nervous system. It causes gallbladder contraction, release of pancreatic exocrine (or digestive) enzymes, and affects other gastrointestinal functions. Cholecystokinin may be the mediator of satiety. Pancreozymin,CCK-33,Cholecystokinin 33,Uropancreozymin
D002795 Choline O-Acetyltransferase An enzyme that catalyzes the formation of acetylcholine from acetyl-CoA and choline. EC 2.3.1.6. Choline Acetylase,Choline Acetyltransferase,Acetylase, Choline,Acetyltransferase, Choline,Choline O Acetyltransferase,O-Acetyltransferase, Choline
D003704 Dementia An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness. Senile Paranoid Dementia,Amentia,Familial Dementia,Amentias,Dementia, Familial,Dementias,Dementias, Familial,Dementias, Senile Paranoid,Familial Dementias,Paranoid Dementia, Senile,Paranoid Dementias, Senile,Senile Paranoid Dementias
D004355 Drug Stability The chemical and physical integrity of a pharmaceutical product. Drug Shelf Life,Drugs Shelf Lives,Shelf Life, Drugs,Drug Stabilities,Drugs Shelf Life,Drugs Shelf Live,Life, Drugs Shelf,Shelf Life, Drug,Shelf Live, Drugs,Shelf Lives, Drugs
D006624 Hippocampus A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation. Ammon Horn,Cornu Ammonis,Hippocampal Formation,Subiculum,Ammon's Horn,Hippocampus Proper,Ammons Horn,Formation, Hippocampal,Formations, Hippocampal,Hippocampal Formations,Hippocampus Propers,Horn, Ammon,Horn, Ammon's,Proper, Hippocampus,Propers, Hippocampus,Subiculums
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen
Reduced cortical choline acetyltransferase activity in senile dementia of Alzheimer type is not accompanied by changes in vasoactive intestinal polypeptide.
November 1980, Brain research,
M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen
Corticotropin-releasing factor-like immunoreactivity in senile dementia of the Alzheimer type. Reduced cortical and striatal concentrations.
December 1985, JAMA,
M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen
Arginine vasopressin and choline acetyltransferase in brains of patients with Alzheimer type senile dementia.
January 1980, Lancet (London, England),
M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen
Cortical somatostatin-like immunoreactivity in cases of Alzheimer's disease and senile dementia of the Alzheimer type.
January 1981, Neurobiology of aging,
M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen
Loss of choline acetyltransferase activity in normal aging and in senile dementia.
January 1978, Advances in experimental medicine and biology,
M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen
Cortical substance P-like immunoreactivity in cases of Alzheimer's disease and senile dementia of the Alzheimer type.
June 1982, Journal of neurochemistry,
M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen
Qualitative abnormalities of choline acetyltransferase in Alzheimer type dementia.
December 1986, Journal of the neurological sciences,
M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen
Reduced cortical choline acetyltransferase activity in Gerstmann-Sträussler syndrome.
January 1982, Progress in neuro-psychopharmacology & biological psychiatry,
M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen
Olfactory tubercle choline acetyltransferase activity in Alzheimer-type dementia, Down's syndrome and Huntington's chorea.
October 1984, Journal of neurology, neurosurgery, and psychiatry,
M N Rossor, and J F Rehfeld, and P C Emson, and C Q Mountjoy, and M Roth, and L L Iversen
Choline acetyltransferase immunoreactivity in neuritic plaques of Alzheimer brain.
November 1986, Neuroscience letters,
Copied contents to your clipboard!