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The effectiveness of synthetic blood group A and B immunoadsorbents in removing anti-A and anti-B from human sera was evaluated. The sera contained specific alloantibodies and were destined for use as diagnostic reagents. Both Synsorb-A(TM) and Synsorb-B(TM) removed all saline anti-A or anti-B activity from 20 sera tested. All trace of anti-A activity detectable by the indirect antiglobulin test was removed from only 20% of sera; anti-B with similar reactivity was removed from 66% of sera. Specific (wanted) alloantibody titres were reduced by synsorb-A in 60% of sera, but were unaffected by Synsorb-B. Despite these shortcomings, such immunoadsorbents are of value particularly when cells of appropriate phenotype are unavailable for absorptions.
G Crawford, and
A Adatia, and
D H Naylor, and
B P Moore
April 1988,
Behring Institute Mitteilungen,
G Crawford, and
A Adatia, and
D H Naylor, and
B P Moore
July 1983,
American journal of clinical pathology,
G Crawford, and
A Adatia, and
D H Naylor, and
B P Moore
January 1991,
Bioconjugate chemistry,
G Crawford, and
A Adatia, and
D H Naylor, and
B P Moore
January 1980,
Transactions - American Society for Artificial Internal Organs,
G Crawford, and
A Adatia, and
D H Naylor, and
B P Moore
December 1989,
The International journal of artificial organs,
G Crawford, and
A Adatia, and
D H Naylor, and
B P Moore
April 1983,
Nihon hoigaku zasshi = The Japanese journal of legal medicine,
G Crawford, and
A Adatia, and
D H Naylor, and
B P Moore
February 1966,
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles,
G Crawford, and
A Adatia, and
D H Naylor, and
B P Moore
October 2009,
Biotechnology journal,
G Crawford, and
A Adatia, and
D H Naylor, and
B P Moore
August 2015,
Zhongguo shi yan xue ye xue za zhi,
G Crawford, and
A Adatia, and
D H Naylor, and
B P Moore
August 2010,
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,
