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In 10 female patients with classical rheumatoid arthritis D-penicillamine was administered in a daily dose of 150-150 mg for 4 months. The only additional antiphlogistic treatment was indomethacin (100-150 mg daily). At the beginning and during the trial blood (total) levels of zinc with n-activation analysis and the excretion with urine were determined using n-activationanaysis and atom absorption. By spectrometry following results were obtained: an increase of zinc excretion. By spectrometry following results were obtained: in increase of zinc excretion in urine until day 21; after 2 and 4 months decreased above levels at the original value before beginning of treatment. Blood levels of zinc decreased distinctly until the 2nd week, increase at the 3rd week and return to the original value of the controls before D-penicillamine therapy at the 2nd and 4th months.
D K Teherani, and
H Altmann, and
G Tausch, and
R Eberl
April 1998,
British journal of rheumatology,
D K Teherani, and
H Altmann, and
G Tausch, and
R Eberl
June 1979,
Clinica chimica acta; international journal of clinical chemistry,
D K Teherani, and
H Altmann, and
G Tausch, and
R Eberl
December 1978,
The Nebraska medical journal,
D K Teherani, and
H Altmann, and
G Tausch, and
R Eberl
November 1971,
Arzneimittel-Forschung,
D K Teherani, and
H Altmann, and
G Tausch, and
R Eberl
January 1975,
Journal belge de rhumatologie et de medecine physique = Belgisch tijdschrift voor reumatologie en fysische geneeskunde,
D K Teherani, and
H Altmann, and
G Tausch, and
R Eberl
January 1983,
Terapevticheskii arkhiv,
D K Teherani, and
H Altmann, and
G Tausch, and
R Eberl
January 1972,
Reumatologia,
D K Teherani, and
H Altmann, and
G Tausch, and
R Eberl
January 1975,
Terapevticheskii arkhiv,
D K Teherani, and
H Altmann, and
G Tausch, and
R Eberl
January 1978,
Medicinski arhiv,
D K Teherani, and
H Altmann, and
G Tausch, and
R Eberl
June 1974,
Der Internist,
