Leukocyte locomotion and regulative serum effects in rheumatoid arthritis. 1981

G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen

Leukocyte locomotion (LL) of 40 patients with rheumatoid arthritis (RA) was found to be unimpaired as compared to LL of 23 control individuals (p Greater Than 0.2). Casein and zymosan activated human sera were used as cytotaxins, and the sera of RA patients proved to be activatable in the same way as control sera in that they produced a similar chemotactic activity (p Greater Than 0.2). However, RA sera inhibited LL significantly (p Less Than 0.01) in comparison to control sera. This phenomenon was unchanged after elimination of immune complexes be ultracentrifugation, but could be reversed, after incubation of cells with RA sera, by reincubation with control sera.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002634 Chemotaxis, Leukocyte The movement of leukocytes in response to a chemical concentration gradient or to products formed in an immunologic reaction. Leukotaxis,Leukocyte Chemotaxis
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D001172 Arthritis, Rheumatoid A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. Rheumatoid Arthritis
D012217 Rheumatoid Factor Autoantibodies found in adult RHEUMATOID ARTHRITIS patients that are directed against GAMMA-CHAIN IMMUNOGLOBULINS. Factor, Rheumatoid

Related Publications

G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen
June 1989, Acta orthopaedica Scandinavica,
G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen
February 2006, Pathophysiology : the official journal of the International Society for Pathophysiology,
G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen
January 1976, Arthritis and rheumatism,
G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen
January 1984, International archives of allergy and applied immunology,
G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen
January 1990, The Turkish journal of pediatrics,
G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen
October 1978, La Nouvelle presse medicale,
G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen
August 2017, Rheumatic diseases clinics of North America,
G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen
December 1972, Polski tygodnik lekarski (Warsaw, Poland : 1960),
G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen
January 1979, The Journal of rheumatology,
G Lanzer, and C Zielinski, and W Knapp, and R Eberl, and C Steffen
January 1980, Reviews of infectious diseases,
Copied contents to your clipboard!