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An unknown compound containing glutamic acid residue was found in newborn rat brain. The compound occurred predominantly in brain. Its concentration was approx. 1 mumol/g tissue at birth and decreased to one-tenth 24 days after birth. The compound was isolated from newborn rat brains, and subjected to elementary analysis and to infrared and mass spectrometric analysis. Glutamic acid and citric acid were formed from the compound on acid hydrolysis. The compound was presumed to be a citrylglutamic acid. Two isomers, alpha- and beta-citrylglutamic acid, were synthesized. The unknown compound was identified as beta-citryl-L-glutamic acid. The occurence of this compound has not been reported in nature.
M Miyake, and
Y Kakimoto, and
M Sorimachi
November 1964,
Biochimica et biophysica acta,
M Miyake, and
Y Kakimoto, and
M Sorimachi
October 1978,
FEBS letters,
M Miyake, and
Y Kakimoto, and
M Sorimachi
July 1995,
Biochimica et biophysica acta,
M Miyake, and
Y Kakimoto, and
M Sorimachi
May 1965,
Biochimica et biophysica acta,
M Miyake, and
Y Kakimoto, and
M Sorimachi
May 1989,
Neuroscience letters,
M Miyake, and
Y Kakimoto, and
M Sorimachi
February 1966,
Seikagaku. The Journal of Japanese Biochemical Society,
M Miyake, and
Y Kakimoto, and
M Sorimachi
July 1979,
Journal of neurochemistry,
M Miyake, and
Y Kakimoto, and
M Sorimachi
May 1989,
Biochemical and biophysical research communications,
M Miyake, and
Y Kakimoto, and
M Sorimachi
October 1982,
Biochemical and biophysical research communications,
M Miyake, and
Y Kakimoto, and
M Sorimachi
April 1982,
Biochemical and biophysical research communications,
