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Thyroid function and scans were evaluated in fifty disease-free patients 2 to 16 years after receiving neck irradiation for the treatment of Hodgkin's disease. Twenty-five of 50 patients had abnormal thyroid studies: eight were hypothyroid, two were hypothyroid and had abnormal scans, and fifteen had abnormal scans. Of the 15 patients with abnormal scans, one had an isolated elevation of TSH (thyroid stimulating hormone) and one developed exophthalmos. These data, obtained within a relatively short follow-up period, indicate that morphologic and functional abnormalities of the thyroid gland are not uncommon in patients who have received irradiation to the thyroid gland in the course of treatment for Hodgkin's disease. There is need for continuous reevaluation of the thyroid status in such patients.
D F Nelson, and
K V Reddy, and
R E O'Mara, and
P Rubin
September 1977,
Clinical radiology,
D F Nelson, and
K V Reddy, and
R E O'Mara, and
P Rubin
January 1988,
Journal of the Royal Society of Medicine,
D F Nelson, and
K V Reddy, and
R E O'Mara, and
P Rubin
January 1998,
Radiation medicine,
D F Nelson, and
K V Reddy, and
R E O'Mara, and
P Rubin
January 1981,
New York state journal of medicine,
D F Nelson, and
K V Reddy, and
R E O'Mara, and
P Rubin
March 1990,
Journal of endocrinological investigation,
D F Nelson, and
K V Reddy, and
R E O'Mara, and
P Rubin
January 1984,
Acta medica Scandinavica,
D F Nelson, and
K V Reddy, and
R E O'Mara, and
P Rubin
September 1978,
JAMA,
D F Nelson, and
K V Reddy, and
R E O'Mara, and
P Rubin
August 1979,
Cancer treatment reports,
D F Nelson, and
K V Reddy, and
R E O'Mara, and
P Rubin
August 1979,
Collected works on cardio-pulmonary disease,
D F Nelson, and
K V Reddy, and
R E O'Mara, and
P Rubin
November 1983,
Nederlands tijdschrift voor geneeskunde,
