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Five groups of rats exposed to varying doses of lead by gastric intubation from Day 3 to Day 30 of life were tested to determine whether lead affects memory. A variable intertrial interval spatial alternation task was used to examine memory; it permits generation of a complete retention curve within subjects in a single session. Because of lead's putative effects on the cholinergic neuronal system, the cholinergic drugs controls to the drugs and to compare drug effects with lead effects. Orderly memory functions were obtained in all animals; however lead-exposed groups did not differ in performance from controls. Scoopolamine decreased alternation accuracy but its effects did not differ across the neonatal dose groups.
K S Milar, and
M R Krigman, and
L D Grant
January 1983,
Neurobehavioral toxicology and teratology,
K S Milar, and
M R Krigman, and
L D Grant
January 1983,
Neurobehavioral toxicology and teratology,
K S Milar, and
M R Krigman, and
L D Grant
October 1983,
Nihon eiseigaku zasshi. Japanese journal of hygiene,
K S Milar, and
M R Krigman, and
L D Grant
September 1977,
Toxicology and applied pharmacology,
K S Milar, and
M R Krigman, and
L D Grant
September 2017,
Neurotoxicology,
K S Milar, and
M R Krigman, and
L D Grant
May 2022,
Molecular neurobiology,
K S Milar, and
M R Krigman, and
L D Grant
July 2006,
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases,
K S Milar, and
M R Krigman, and
L D Grant
May 1994,
Fundamental and applied toxicology : official journal of the Society of Toxicology,
K S Milar, and
M R Krigman, and
L D Grant
October 2008,
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine],
K S Milar, and
M R Krigman, and
L D Grant
March 2005,
Occupational and environmental medicine,
