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In this search the serum and dialysis fluid of psoriasic patients in comparison with those of normal and uremic subjects have been evaluated by gel-filtration through a Sephadex G-15 column. The results showed a storage of the substances with various molecular weight in these patients. Particular attention was addressed to those with MW less than 1500 because they are not generally present in the normal subjects, decrease in the serum of psoriasic and uremic patients during the dialytic therapy, simultaneously with positive effects on the clinical symptomatology.
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