-transparent.png){kind=logo}
The effect of various drugs was studied on 3-methoxytyramine (3-MT) concentrations in rat striatum. The drugs were chosen for their ability to interfere with the dopaminergic system at different levels. Dopamine (DA) acidic metabolites, i.e. homovanillic acid (HVA) and 3,4-dihydroxyphenylacetic acid (DOPAC), were also measured. Changes of 3-MT, unlike those of DOPAC and HVA, seem to reflect the functional activity of dopaminergic neurons. In fact drugs believed to increase or decrease DA content in the synaptic cleft produce predictable changes of striatal 3-MT. Thus cocaine, nomifensine and d-amphetamine increase 3-MT concentrations while gamma-butyrolactone, alpha-methyltyrosine and apomorphine decrease it.
A M Di Giulio, and
A Groppetti, and
F Cattabeni, and
C L Galli, and
A Maggi, and
S Algeri, and
F Ponzio
July 1977,
Activitas nervosa superior,
A M Di Giulio, and
A Groppetti, and
F Cattabeni, and
C L Galli, and
A Maggi, and
S Algeri, and
F Ponzio
September 1974,
Harefuah,
A M Di Giulio, and
A Groppetti, and
F Cattabeni, and
C L Galli, and
A Maggi, and
S Algeri, and
F Ponzio
January 1997,
Neurotoxicology and teratology,
A M Di Giulio, and
A Groppetti, and
F Cattabeni, and
C L Galli, and
A Maggi, and
S Algeri, and
F Ponzio
January 1997,
Journal of neural transmission. Supplementum,
A M Di Giulio, and
A Groppetti, and
F Cattabeni, and
C L Galli, and
A Maggi, and
S Algeri, and
F Ponzio
April 1986,
Journal of neurochemistry,
A M Di Giulio, and
A Groppetti, and
F Cattabeni, and
C L Galli, and
A Maggi, and
S Algeri, and
F Ponzio
January 2002,
Neuroscience and behavioral physiology,
A M Di Giulio, and
A Groppetti, and
F Cattabeni, and
C L Galli, and
A Maggi, and
S Algeri, and
F Ponzio
January 2007,
Uspekhi fiziologicheskikh nauk,
A M Di Giulio, and
A Groppetti, and
F Cattabeni, and
C L Galli, and
A Maggi, and
S Algeri, and
F Ponzio
March 1977,
European journal of pharmacology,
A M Di Giulio, and
A Groppetti, and
F Cattabeni, and
C L Galli, and
A Maggi, and
S Algeri, and
F Ponzio
May 1976,
Molecular pharmacology,
A M Di Giulio, and
A Groppetti, and
F Cattabeni, and
C L Galli, and
A Maggi, and
S Algeri, and
F Ponzio
April 2017,
ACS chemical neuroscience,
