-transparent.png){kind=logo}
We report on 4 cases of reversible acute renal failure (ARF), appearing within the first days after institution of a sulfinpyrazone treatment (600 mg p. day) early after a myocardial infarction. Urinary data were consistent with an acute tubular necrosis. A renal biopsy, performed in 3 patients, revealed only very discrete tubular and interstitial lesions, not helpful in the understanding of the ARF. Three pathogenetic mechanisms could be evoked. Data in favour of an acute tubular precipitation of uric acid or an immunologically induced acute interstitial nephritis are lacking. More probably this ARF is due to an inhibitory effect of sulfinpyrazone on the renal prostaglandin synthesis. Early after a myocardial infarction, renal prostaglandins could play an important protective role in maintaining the renal circulation. Renal function should be monitored closely when sulfinpyrazone is prescribed, especially early after a myocardial infarction.
J Boelaert, and
A Meyrier, and
J D Sraer, and
L Morel-Maroger, and
O Kourilsky, and
S Dard, and
M El Nahas, and
P Van Eeghem, and
R Daneels
July 1982,
Deutsche medizinische Wochenschrift (1946),
J Boelaert, and
A Meyrier, and
J D Sraer, and
L Morel-Maroger, and
O Kourilsky, and
S Dard, and
M El Nahas, and
P Van Eeghem, and
R Daneels
July 1983,
Clinical nephrology,
J Boelaert, and
A Meyrier, and
J D Sraer, and
L Morel-Maroger, and
O Kourilsky, and
S Dard, and
M El Nahas, and
P Van Eeghem, and
R Daneels
July 1981,
Connecticut medicine,
J Boelaert, and
A Meyrier, and
J D Sraer, and
L Morel-Maroger, and
O Kourilsky, and
S Dard, and
M El Nahas, and
P Van Eeghem, and
R Daneels
October 1979,
Lijecnicki vjesnik,
J Boelaert, and
A Meyrier, and
J D Sraer, and
L Morel-Maroger, and
O Kourilsky, and
S Dard, and
M El Nahas, and
P Van Eeghem, and
R Daneels
April 1982,
South Dakota journal of medicine,
J Boelaert, and
A Meyrier, and
J D Sraer, and
L Morel-Maroger, and
O Kourilsky, and
S Dard, and
M El Nahas, and
P Van Eeghem, and
R Daneels
May 1998,
The American journal of the medical sciences,
J Boelaert, and
A Meyrier, and
J D Sraer, and
L Morel-Maroger, and
O Kourilsky, and
S Dard, and
M El Nahas, and
P Van Eeghem, and
R Daneels
November 1976,
Langenbecks Archiv fur Chirurgie,
J Boelaert, and
A Meyrier, and
J D Sraer, and
L Morel-Maroger, and
O Kourilsky, and
S Dard, and
M El Nahas, and
P Van Eeghem, and
R Daneels
October 1978,
Lijecnicki vjesnik,
J Boelaert, and
A Meyrier, and
J D Sraer, and
L Morel-Maroger, and
O Kourilsky, and
S Dard, and
M El Nahas, and
P Van Eeghem, and
R Daneels
August 1975,
Thoraxchirurgie, vaskulare Chirurgie,
J Boelaert, and
A Meyrier, and
J D Sraer, and
L Morel-Maroger, and
O Kourilsky, and
S Dard, and
M El Nahas, and
P Van Eeghem, and
R Daneels
September 1983,
Clinical nephrology,
