Biomaterial Database

[Pathogenicity, immunogenic properties and antigenic structure of domestic strains of Trichophyton verrucosum]. 1981

T Kocik

The studies involved 37 domestic strains of the Trichophyton verrucosum species, which plays a dominating role in the etiology of skin mycosis in cattle. The pathogenesis of these strains was determined in guinea-pigs and calves, as well as their immunogenicity and antigenic structure. Differences in pathogenic properties of the individual strains were found both for guinea-pigs and calves. By the method of successive reinfections it was shown that trichophytosis cannot be evoked in guinea-pigs for the second time, and no relationship was found between the presence of antibodies in the serum of the animals and their immunity. Differences of antibodies were detected. However, no correlation between this feature and the virulence of the strain was found. Differences in the activity of extracts according to Fuller from the individual strains were observed in relation to positive rabbit serum against T. verrucosum, strain No 43. The comparison of the antigenic structure of the strains studied showed that they are identical. The methods used made it possible to distinguish 6 antigen fractions, of which fraction III was found in 78% of strains. The author did not succeed in identifying a specific antigen common for all T. verrucosum strains studied. From the analysis of the properties studied, only one strain (No 8) was isolated of 37 T. verrucosum strains, which is useful in every respect for production of live vaccine against trichophytosis.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D002417	Cattle	Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.	Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D002418	Cattle Diseases	Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus.	Bovine Diseases,Bovine Disease,Cattle Disease,Disease, Bovine,Disease, Cattle,Diseases, Bovine,Diseases, Cattle
D005260	Female		Females
D006168	Guinea Pigs	A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.	Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D006388	Hemagglutinins	Agents that cause agglutination of red blood cells. They include antibodies, blood group antigens, lectins, autoimmune factors, bacterial, viral, or parasitic blood agglutinins, etc.	Isohemagglutinins,Exohemagglutinins,Hemagglutinin
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000908	Antibodies, Fungal	Immunoglobulins produced in a response to FUNGAL ANTIGENS.	Fungal Antibodies
D000946	Antigens, Fungal	Substances of fungal origin that have antigenic activity.	Fungal Antigen,Fungal Antigens,Antigen, Fungal
D014005	Tinea	Fungal infection of keratinized tissues such as hair, skin and nails. The main causative fungi include MICROSPORUM; TRICHOPHYTON; and EPIDERMOPHYTON.	Dermatophytoses,Epidermophytosis,Ringworm,Tinea Corporis,Trichophytosis,Dermatophytosis,Trichophyton mentagrophytes Infection,Epidermophytoses,Infection, Trichophyton mentagrophytes,Tineas,Trichophyton mentagrophytes Infections,Trichophytoses