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No abolition of functions from the clinical aspect was detected in most patients with tonsillectomies or adenotomies although there are some reports that tonsillectomy increases the susceptibility to subsequent development of Hodgkin's disease by 2.9 fold. Sequential investigations on the responsiveness of lymphocytes to various mitogens, and quantitative estimations of immunoglobulins and other humoral factors were carried out in 54 tonsillectomized and/or adenotomized patients of either sex between the ages of 4 and 55. The present findings showed abnormalities in lymphocyte responses to mitogens and the production of humoral factors in a few young patients post operatively, although they were not detected in adult patients during sequential observations.
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