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Outbred and inbred (Hartley strain) guinea pigs (GP) were inoculated intragastrically with pathogenic and nonpathogenic Treponema hyodysenteriae. GP 3 to 16 weeks old received T. hyodysenteriae after a fasting period of 36 to 72 h. Infected GP with pathogenic T. hyodysenteriae developed a diarrheal and/or depressive condition, with mucus but not blood in the feces. Of 88 GP, 40 had gross lesions resembling those of swine dysentery. Lesions were limited mainly to the large intestine. TP used as controls or inoculated with nonpathogenic T. hyodysenteriae did not develop these lesions in the large intestine. These studies suggest that the GP may be used as an animal model for swine dysentery.
L A Joens, and
J G Songer, and
D L Harris, and
R D Glock
August 1979,
Infection and immunity,
L A Joens, and
J G Songer, and
D L Harris, and
R D Glock
July 1983,
Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious...,
L A Joens, and
J G Songer, and
D L Harris, and
R D Glock
August 1984,
Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology,
L A Joens, and
J G Songer, and
D L Harris, and
R D Glock
April 1978,
American journal of veterinary research,
L A Joens, and
J G Songer, and
D L Harris, and
R D Glock
August 1980,
American journal of veterinary research,
L A Joens, and
J G Songer, and
D L Harris, and
R D Glock
January 1985,
Microbiology and immunology,
L A Joens, and
J G Songer, and
D L Harris, and
R D Glock
December 1979,
Infection and immunity,
L A Joens, and
J G Songer, and
D L Harris, and
R D Glock
January 1979,
Acta veterinaria Scandinavica,
L A Joens, and
J G Songer, and
D L Harris, and
R D Glock
October 1985,
Canadian journal of comparative medicine : Revue canadienne de medecine comparee,
L A Joens, and
J G Songer, and
D L Harris, and
R D Glock
April 1985,
Genitourinary medicine,
