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The in vitro response to sheep erythrocytes of mesenteric lymph node cells from mice infected with the larval cestode Taenia crassiceps is significantly depressed and can be restored to control levels by addition of activated peritoneal cells depleted of functional T or B lymphocytes. Adherent mesenteric lymph node cells from infected mice are unable to reconstitute the in vitro response to sheep erythrocytes of normal nonadherent cells. The responses of mesenteric lymph node cells from infected mice to the T-lymphocyte mitogens concanavalin A and phytohemagglutinin and the B-lymphocyte mitogen lipopolysaccharide are normal. Mesenteric lymph node cells from infected mice do not suppress the in vitro response to sheep erythrocytes of normal mesenteric lymph node cells. These results suggest that the immunodepression in T. crassiceps-infected mice is primarily the result of alterations in functional accessory cells.
K L Miller, and
A H Good, and
R I Mishell
January 2021,
Frontiers in cellular and infection microbiology,
K L Miller, and
A H Good, and
R I Mishell
January 1992,
Deutsche medizinische Wochenschrift (1946),
K L Miller, and
A H Good, and
R I Mishell
June 1971,
Nature: New biology,
K L Miller, and
A H Good, and
R I Mishell
November 1984,
Biochemical and biophysical research communications,
K L Miller, and
A H Good, and
R I Mishell
July 1992,
Molecular and biochemical parasitology,
K L Miller, and
A H Good, and
R I Mishell
December 2009,
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases,
K L Miller, and
A H Good, and
R I Mishell
February 2014,
Experimental parasitology,
K L Miller, and
A H Good, and
R I Mishell
April 1976,
International journal for parasitology,
K L Miller, and
A H Good, and
R I Mishell
November 1976,
European journal of immunology,
K L Miller, and
A H Good, and
R I Mishell
March 2010,
Parasitology,
