[Serological diagnosis of syphilis by the SPHA test (author's transl)]. 1981

A Luger, and F Gschnait, and B L Schmidt

Despite the availability of a broad spectrum of specific and non-specific tests for the serodiagnosis of syphilis, the interpretation of the results may be difficult and may frequently not provide sufficient information for a precise decision on the needs for antisyphilitic treatment. The present paper reports on the serological IgM tests (IgM-FTA-ABS; 19S-IgM-FTA-ABS) and, in particular, on the newly-developed SPHA test (solid phase hemadsorption). Present experience indicates that for the first time in syphilis serology this test unifies the advantages of high specificity, high sensitivity, low costs and extraordinary clinical value for the decision whether or not the patient needs antisyphilitic treatment.

UI MeSH Term Description Entries
D007075 Immunoglobulin M A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally was called a macroglobulin. Gamma Globulin, 19S,IgM,IgM Antibody,IgM1,IgM2,19S Gamma Globulin,Antibody, IgM
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006382 Hemadsorption A phenomenon manifested by an agent or substance adhering to or being adsorbed on the surface of a red blood cell, as tuberculin can be adsorbed on red blood cells under certain conditions. (Stedman, 25th ed) Hemadsorptions
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013587 Syphilis A contagious venereal disease caused by the spirochete TREPONEMA PALLIDUM. Great Pox
D013588 Syphilis Serodiagnosis Serologic tests for syphilis. Kahn Test,Wassermann Reaction,Serodiagnosis, Syphilis,Reaction, Wassermann,Serodiagnoses, Syphilis,Syphilis Serodiagnoses,Test, Kahn

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