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Transport kinetics of urea and creatinine across the cell wall was investigated on the model of azotaemic erythrocytes. Urea was found to pass rapidly across the cell membrane whilst the transport of creatinine is delayed to a calculated half time of approximately 12 minutes. Transport of metabolites play an important role in dialysis efficacy. the significance of transcellular transport kinetics of different molecules with respect to dialysis strategy is discussed.
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