Biomaterial Database

[Internal inhibition in rats after destruction of amygdaloid complex nuclei]. 1981

P G Bogach, and N E Makarchuk, and G M Chaĭchenko

In experiments on male albino rats bilateral lesions of the basolateral amygdala (BLA) impaired extinction and differentiation of the food-procuring conditioned reflexes where as bilateral corticomedial (CMA) lesions had no effect on them. The BLA damage caused a significant impairment of the aversive stimuli discrimination but had no effect on the extinction of the conditioned avoidance reflex in a shuttle-box. The CMA lesions in both hemispheres led to attenuation of aversive stimuli discrimination and delay of avoidance extinction. The data obtained testify to the BLA dominant role in internal inhibition of the alimentary conditioned reflexes and the CMA dominant role in internal inhibition of avoidance conditioning and furthermore to the importance of BLA in the evaluation of the emotional significance and biological validity of the stimuli (reward or punishment).

UI	MeSH Term	Description	Entries
D007266	Inhibition, Psychological	The interference with or prevention of a behavioral or verbal response even though the stimulus for that response is present; in psychoanalysis the unconscious restraining of an instinctual process.	Inhibition (Psychology),Inhibition, Psychology,Psychological Inhibition,Inhibitions (Psychology),Inhibitions, Psychological,Inhibitions, Psychology,Psychological Inhibitions,Psychology Inhibition,Psychology Inhibitions
D008297	Male		Males
D010897	Pitch Discrimination	The ability to differentiate sound frequency or pitch.	Discrimination, Pitch,Pitch Discriminations
D001931	Brain Mapping	Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.	Brain Electrical Activity Mapping,Functional Cerebral Localization,Topographic Brain Mapping,Brain Mapping, Topographic,Functional Cerebral Localizations,Mapping, Brain,Mapping, Topographic Brain
D003216	Conditioning, Operant	Learning situations in which the sequence responses of the subject are instrumental in producing reinforcement. When the correct response occurs, which involves the selection from among a repertoire of responses, the subject is immediately reinforced.	Instrumental Learning,Learning, Instrumental,Operant Conditioning,Conditionings, Operant,Instrumental Learnings,Learnings, Instrumental,Operant Conditionings
D004193	Discrimination Learning	Learning that is manifested in the ability to respond differentially to various stimuli.	Discriminative Learning,Discrimination Learnings,Discriminative Learnings,Learning, Discrimination,Learning, Discriminative
D005108	Extinction, Psychological	The procedure of presenting the conditioned stimulus without REINFORCEMENT to an organism previously conditioned. It refers also to the diminution of a conditioned response resulting from this procedure.	Psychological Extinction,Extinction (Psychology),Extinctions (Psychology),Extinctions, Psychological,Psychological Extinctions
D005502	Food	Substances taken in by the body to provide nourishment.	Foods
D000679	Amygdala	Almond-shaped group of basal nuclei anterior to the INFERIOR HORN OF THE LATERAL VENTRICLE of the TEMPORAL LOBE. The amygdala is part of the limbic system.	Amygdaloid Body,Amygdaloid Nuclear Complex,Amygdaloid Nucleus,Archistriatum,Corpus Amygdaloideum,Intercalated Amygdaloid Nuclei,Massa Intercalata,Nucleus Amygdalae,Amygdalae, Nucleus,Amygdaloid Bodies,Amygdaloid Nuclear Complices,Amygdaloid Nuclei, Intercalated,Amygdaloid Nucleus, Intercalated,Amygdaloideum, Corpus,Amygdaloideums, Corpus,Archistriatums,Complex, Amygdaloid Nuclear,Complices, Amygdaloid Nuclear,Corpus Amygdaloideums,Intercalata, Massa,Intercalatas, Massa,Intercalated Amygdaloid Nucleus,Massa Intercalatas,Nuclear Complex, Amygdaloid,Nuclear Complices, Amygdaloid,Nuclei, Intercalated Amygdaloid,Nucleus, Amygdaloid,Nucleus, Intercalated Amygdaloid
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia