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Male rats were trained to swim for 9-10 days to assess the effect of chronic stress on the capacity and affinity of specific glucocorticoid binding in the cytosol fraction of myocardial tissue. A significant decrease in the binding capacity for corticosterone (Cpd B) was found 24 hours after the last swimming test, while the affinity constant remained unchanged. Contrary to Cpd B binding, there was no change in the capacity of dexamethasone binding, and there was no decrease in the Cpd B binding capacity in rats which had been adrenalectomized 2 days prior to the training period. We conclude that daily swimming for 9-10 days alters the numbers of cytoplasmic Cpd B binding sites in the face of increased adrenocortical activity, while not affecting dexamethasone binding in the cytosol fraction of myocardial tissue.
A Eller, and
C Nyakas, and
G Szabó, and
E Endröczi
January 1985,
Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia,
A Eller, and
C Nyakas, and
G Szabó, and
E Endröczi
January 1988,
Physiology & behavior,
A Eller, and
C Nyakas, and
G Szabó, and
E Endröczi
November 1982,
Acta endocrinologica,
A Eller, and
C Nyakas, and
G Szabó, and
E Endröczi
January 1991,
Life sciences,
A Eller, and
C Nyakas, and
G Szabó, and
E Endröczi
August 1990,
Experimental and clinical endocrinology,
A Eller, and
C Nyakas, and
G Szabó, and
E Endröczi
January 1991,
Biulleten' eksperimental'noi biologii i meditsiny,
A Eller, and
C Nyakas, and
G Szabó, and
E Endröczi
April 1988,
Neuroscience letters,
A Eller, and
C Nyakas, and
G Szabó, and
E Endröczi
May 1977,
Experientia,
A Eller, and
C Nyakas, and
G Szabó, and
E Endröczi
June 2000,
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,
A Eller, and
C Nyakas, and
G Szabó, and
E Endröczi
August 1982,
The American journal of physiology,
