Biomaterial Database

Study of nonspecific lymphocyte transformation in urologic cancer patients. 1978

I Romics, and J Horváth

Blast-cell transformation of lymphocytes in response to phytohaemagglutinin was examined in patients with urologic tumours and with nonmalignant urologic processes. A significant depression of immune reactivity was found in the malignant cases. The practical aspects of the findings are discussed.

UI	MeSH Term	Description	Entries
D008213	Lymphocyte Activation	Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.	Blast Transformation,Blastogenesis,Lymphoblast Transformation,Lymphocyte Stimulation,Lymphocyte Transformation,Transformation, Blast,Transformation, Lymphoblast,Transformation, Lymphocyte,Activation, Lymphocyte,Stimulation, Lymphocyte
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010835	Phytohemagglutinins	Mucoproteins isolated from the kidney bean (Phaseolus vulgaris); some of them are mitogenic to lymphocytes, others agglutinate all or certain types of erythrocytes or lymphocytes. They are used mainly in the study of immune mechanisms and in cell culture.	Kidney Bean Lectin,Kidney Bean Lectins,Lectins, Kidney Bean,Phaseolus vulgaris Lectin,Phaseolus vulgaris Lectins,Phytohemagglutinin,Hemagglutinins, Plant,Lectin, Kidney Bean,Lectin, Phaseolus vulgaris,Lectins, Phaseolus vulgaris,Plant Hemagglutinins
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014571	Urologic Neoplasms	Tumors or cancer of the URINARY TRACT in either the male or the female.	Cancer of Urinary Tract,Urinary Tract Cancer,Urologic Cancer,Cancer of the Urinary Tract,Neoplasms, Urologic,Urinary Tract Neoplasms,Urological Cancer,Urological Neoplasms,Cancer, Urinary Tract,Cancer, Urologic,Cancer, Urological,Cancers, Urinary Tract,Cancers, Urologic,Cancers, Urological,Neoplasm, Urinary Tract,Neoplasm, Urologic,Neoplasm, Urological,Neoplasms, Urinary Tract,Neoplasms, Urological,Tract Neoplasm, Urinary,Tract Neoplasms, Urinary,Urinary Tract Cancers,Urinary Tract Neoplasm,Urologic Cancers,Urologic Neoplasm,Urological Cancers,Urological Neoplasm