-transparent.png){kind=logo}
Steplike end-tidal hypoxic drives (PETCO2 = 53 Torr) lasting for 5 min were generated in a group of normal subjects and a group of carotid body-resected subjects when end-tidal CO2 was maintained constant under eucapnic (PETCO2 = 39 Torr) and hypercapnic (PETCO2 = 49 Torr) conditions. The hypoxic ventilatory response of the normal subjects was prompt and significant in eucapnia and was enhanced in the hypercapnic state, evidencing CO2-O2 interaction. In contrast, the carotid body-resected subjects did not respond to eucapnic hypoxia but did demonstrate a small but significant ventilatory response to hypoxia against the hypercapnic background. This suggests that the aortic bodies in man may contribute a small component of the hypoxic ventilatory drive under hypercapnic conditions, although the possibility of neuromalike ending regeneration cannot be excluded.
G D Swanson, and
B J Whipp, and
R D Kaufman, and
K A Aqleh, and
B Winter, and
J W Bellville
September 1975,
British journal of anaesthesia,
G D Swanson, and
B J Whipp, and
R D Kaufman, and
K A Aqleh, and
B Winter, and
J W Bellville
June 1970,
The Journal of clinical investigation,
G D Swanson, and
B J Whipp, and
R D Kaufman, and
K A Aqleh, and
B Winter, and
J W Bellville
July 1986,
Respiration physiology,
G D Swanson, and
B J Whipp, and
R D Kaufman, and
K A Aqleh, and
B Winter, and
J W Bellville
November 1979,
Clinical science (London, England : 1979),
G D Swanson, and
B J Whipp, and
R D Kaufman, and
K A Aqleh, and
B Winter, and
J W Bellville
May 1994,
American journal of respiratory and critical care medicine,
G D Swanson, and
B J Whipp, and
R D Kaufman, and
K A Aqleh, and
B Winter, and
J W Bellville
November 1987,
Journal of applied physiology (Bethesda, Md. : 1985),
G D Swanson, and
B J Whipp, and
R D Kaufman, and
K A Aqleh, and
B Winter, and
J W Bellville
November 1971,
The New England journal of medicine,
G D Swanson, and
B J Whipp, and
R D Kaufman, and
K A Aqleh, and
B Winter, and
J W Bellville
July 2001,
Journal of applied physiology (Bethesda, Md. : 1985),
G D Swanson, and
B J Whipp, and
R D Kaufman, and
K A Aqleh, and
B Winter, and
J W Bellville
October 1987,
Respiration physiology,
G D Swanson, and
B J Whipp, and
R D Kaufman, and
K A Aqleh, and
B Winter, and
J W Bellville
February 1984,
Anesthesia and analgesia,
