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Even if different methods were employed in Hb A2 level detection, so far the borderline values between normal and pathological "range" depend on the different laboratories and techniques. The Authors report here an investigation carried out on Hb A2 levels using two different methods: the chromatographic technique by DEAE cellulose column, and the cellulose acetate electrophoresis. The investigation regards 46 normal and 50 beta-thalassemia obligate carrier samples. The results demonstrate that chromatographic technique provides a lowest misclassification rate with a greater reliability. Therefore the use of the microchromatographic procedure for beta-thalassemia screening is recommended.
G Milone, and
A Calaciura, and
P Granata, and
G Sortino
January 1986,
Sangre,
G Milone, and
A Calaciura, and
P Granata, and
G Sortino
January 1966,
Atti della Accademia dei fisiocritici in Siena. Sezione medico-fisica,
G Milone, and
A Calaciura, and
P Granata, and
G Sortino
January 1981,
Sangre,
G Milone, and
A Calaciura, and
P Granata, and
G Sortino
December 2001,
Analytical chemistry,
G Milone, and
A Calaciura, and
P Granata, and
G Sortino
January 1964,
Bollettino dell'Istituto sieroterapico milanese,
G Milone, and
A Calaciura, and
P Granata, and
G Sortino
January 1964,
Acta microbiologica Academiae Scientiarum Hungaricae,
G Milone, and
A Calaciura, and
P Granata, and
G Sortino
March 1975,
Clinical chemistry,
G Milone, and
A Calaciura, and
P Granata, and
G Sortino
December 1966,
The American journal of the medical sciences,
G Milone, and
A Calaciura, and
P Granata, and
G Sortino
January 1973,
Journal of chromatography,
G Milone, and
A Calaciura, and
P Granata, and
G Sortino
January 1965,
Fiziologia normala si patologica,
