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Peritoneal dialysis, hemodialysis, plasma exchange and forced diuresis have been reported to accelerate removal of quinine following quinine poisoning. All these modalities were used simultaneously to treat a 19 year old youth who had become blind as a result of an overdose of quinine tablets. The serum quinine level was measured at 10.5 microgram/ml 13 hours after quinine ingestion. Forced diuresis accounted for the removal of 557 mg of quinine in the first 5 hours and a total of 1625 mg over 75 hours., A 6 hour hemodialysis recovered 30 mg of quinine while peritoneal dialysis removed an average of 1.6 mg/hr over the first 48 hours. Plasmapheresis over 3 hours exchanged 2 liters of plasma containing a total of 8.5 mg of quinine. Some vision returned 19 hours after quinine ingestion but did not become normal until 5 1/2 months later. We conclude that, hemodialysis, peritoneal dialysis and plasma exchange made only a minor contribution to quinine elimination by comparison with renal excretion of quinine.
J K Sabto, and
R M Pierce, and
R H West, and
F W Gurr
January 1968,
The Medical journal of Australia,
J K Sabto, and
R M Pierce, and
R H West, and
F W Gurr
June 1986,
Pediatric clinics of North America,
J K Sabto, and
R M Pierce, and
R H West, and
F W Gurr
January 1970,
Ugeskrift for laeger,
J K Sabto, and
R M Pierce, and
R H West, and
F W Gurr
February 1969,
Minerva medica,
J K Sabto, and
R M Pierce, and
R H West, and
F W Gurr
November 1982,
The New Zealand medical journal,
J K Sabto, and
R M Pierce, and
R H West, and
F W Gurr
March 1984,
Anaesthesia,
J K Sabto, and
R M Pierce, and
R H West, and
F W Gurr
January 1976,
Annals of clinical and laboratory science,
J K Sabto, and
R M Pierce, and
R H West, and
F W Gurr
December 1979,
Wiener medizinische Wochenschrift (1946),
J K Sabto, and
R M Pierce, and
R H West, and
F W Gurr
March 1968,
JAMA,
J K Sabto, and
R M Pierce, and
R H West, and
F W Gurr
January 1986,
Developments in toxicology and environmental science,
