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A quantitative analysis of lipocytes (fat-storing cells, Ito cells) has been conducted on needle liver biopsies of 8 subjects without hepatic impairment. The mean volume density of lipocytes was 1.88 +/- 0.25% of parenchymal volume, and the number of lipocytes per 1,000 hepatocytes (Ito cell index) was 63.45 +/- 19.18. A study of the zonal distribution showed that the values were significantly higher in the centrolobular than in the periportal areas. No correlation was evident between the volume density or the number of lipocytes and the volume density of parenchymal steatosis. The high coefficients of variation resulting from the present study are evidence that quantitative data are necessary to evaluate volumetrical or numerical variations of lipocytes.
M P Giampieri, and
A M Jezequel, and
F Orlandi
November 1966,
Archives of pathology,
M P Giampieri, and
A M Jezequel, and
F Orlandi
December 1985,
Proceedings of the National Academy of Sciences of the United States of America,
M P Giampieri, and
A M Jezequel, and
F Orlandi
January 1992,
Cell motility and the cytoskeleton,
M P Giampieri, and
A M Jezequel, and
F Orlandi
January 1988,
Hepatology (Baltimore, Md.),
M P Giampieri, and
A M Jezequel, and
F Orlandi
February 1992,
Hepatology (Baltimore, Md.),
M P Giampieri, and
A M Jezequel, and
F Orlandi
August 1988,
Gastroenterology,
M P Giampieri, and
A M Jezequel, and
F Orlandi
August 1998,
Hepatology (Baltimore, Md.),
M P Giampieri, and
A M Jezequel, and
F Orlandi
February 1965,
The Journal of laboratory and clinical medicine,
M P Giampieri, and
A M Jezequel, and
F Orlandi
October 1989,
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M P Giampieri, and
A M Jezequel, and
F Orlandi
July 1991,
The Journal of pathology,
