Attempted treatment of canine ehrlichiosis with imidocarb dipropionate. 1981

J Van Heerden, and A Van Heerden

Six clinical and 10 experimentally-induced cases of canine ehrlichiosis were treated with imidocarb dipropionate. The treatment did not result in clinical cure and failed to sterilize the infection. The infection was successfully transmitted from treated dogs to splenectomized and non-splenectomized dogs.

UI MeSH Term Description Entries
D007095 Imidocarb One of ANTIPROTOZOAL AGENTS used especially against BABESIA in livestock. Toxicity has been reported. Imidocarb Dihydrochloride,Imidocarb Hydrochloride,Dihydrochloride, Imidocarb,Hydrochloride, Imidocarb
D008297 Male Males
D002224 Carbanilides Compounds consisting of two phenyl groups joined by a urea. Derivatives may be used as ANTIPARASITIC AGENTS. Diphenylurea Compounds,Compounds, Diphenylurea
D004283 Dog Diseases Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used. Canine Diseases,Canine Disease,Disease, Canine,Disease, Dog,Diseases, Canine,Diseases, Dog,Dog Disease
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D004353 Drug Evaluation, Preclinical Preclinical testing of drugs in experimental animals or in vitro for their biological and toxic effects and potential clinical applications. Drug Screening,Evaluation Studies, Drug, Pre-Clinical,Drug Evaluation Studies, Preclinical,Drug Evaluations, Preclinical,Evaluation Studies, Drug, Preclinical,Evaluation, Preclinical Drug,Evaluations, Preclinical Drug,Medicinal Plants Testing, Preclinical,Preclinical Drug Evaluation,Preclinical Drug Evaluations,Drug Screenings,Screening, Drug,Screenings, Drug
D004536 Ehrlichia Small, often pleomorphic, coccoid to ellipsoidal organisms occurring intracytoplasmically in circulating LYMPHOCYTES. They are the etiologic agents of tick-borne diseases of humans; DOGS; CATTLE; SHEEP; GOATS; and HORSES. Cowdria,Ehrlichia ewingii
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012288 Rickettsiaceae Infections Infections with bacteria of the family RICKETTSIACEAE. Infections, Rickettsiaceae,Infection, Rickettsiaceae,Rickettsiaceae Infection

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