Biomaterial Database

The c-wave of the electroretinogram in vitelliruptive macular degeneration (älvdalssjukan). 1981

K O Skoog, and S E Nilsson

The d.c. ERG and the EOG were recorded from 6 patients with vitelliruptive macular degeneration (VMD, Alvdalssjukan). All EOGs were highly pathological. The a- and b-waves of the ERG were normal. These are pathognomonic findings in VMD, which starts as a generalized disturbance of the pigment epithelium. No signs of a c-wave were seen in 4 patients. Small c-waves occurred in 2 patients, but only under certain stimulus conditions. The major positive component of the c-wave is produced by the pigment epithelium -- receptor complex. Absent or pathological c-waves in VMD, a pigment epithelial disease, are in good agreement with what is known about the origin of the c-wave.

UI	MeSH Term	Description	Entries
D008268	Macular Degeneration	Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.	Maculopathy,Maculopathy, Age-Related,Age-Related Macular Degeneration,Age-Related Maculopathies,Age-Related Maculopathy,Macular Degeneration, Age-Related,Macular Dystrophy,Maculopathies, Age-Related,Age Related Macular Degeneration,Age Related Maculopathies,Age Related Maculopathy,Age-Related Macular Degenerations,Degeneration, Macular,Dystrophy, Macular,Macular Degeneration, Age Related,Macular Degenerations,Macular Dystrophies,Maculopathies,Maculopathy, Age Related
D010857	Pigment Epithelium of Eye	The layer of pigment-containing epithelial cells in the RETINA; the CILIARY BODY; and the IRIS in the eye.	Eye Pigment Epithelium
D004585	Electrooculography	Recording of the average amplitude of the resting potential arising between the cornea and the retina in light and dark adaptation as the eyes turn a standard distance to the right and the left. The increase in potential with light adaptation is used to evaluate the condition of the retinal pigment epithelium.	EOG,Electrooculograms,Electrooculogram
D004596	Electroretinography	Recording of electric potentials in the retina after stimulation by light.	Electroretinographies
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths