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Los Angeles air pollution and asthma in children. 1981

W Richards, and S P Azen, and J Weiss, and S Stocking, and J Church

Indices of air pollution, meteorological conditions and airborne allergens were correlated with emergency room census and hospitalizations for asthma at the Childrens Hospital of Los Angeles (CHLA) during a six-month period encompassing high and low periods of air pollution. In addition, patients in residence at the Sunair Home for Asthmatic Children (SHAC) were studied during a 10-day peak air pollution period. Increases in asthma emergency room visits and hospitalizations correlated significantly with increases in nitric oxide, coefficient of haze, hydrocarbons, Santa Ana wind conditions and total airborne allergen counts. Significant correlations were also found with decreases in ambient levels of O3, SO2, temperature and relative humidity. Among SHAC patients morning peak flow levels were significantly lower during the 10-day peak pollution period than during two control periods of low pollution. However, neither differences in clinical symptoms experienced by these patients nor their need for additional medication were observed.

UI MeSH Term Description Entries
D002140 California State bounded on the east by Nevada and Arizona, on the south by Mexico and the Pacific Ocean on the south and west, and on the north by Oregon.
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D004630 Emergencies Situations or conditions requiring immediate intervention to avoid serious adverse results. Emergency
D006760 Hospitalization The confinement of a patient in a hospital. Hospitalizations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000393 Air Pollutants Any substance in the air which could, if present in high enough concentration, harm humans, animals, vegetation or materials. Substances include GASES; PARTICULATE MATTER; and volatile ORGANIC CHEMICALS. Air Pollutant,Air Pollutants, Environmental,Environmental Air Pollutants,Environmental Pollutants, Air,Air Environmental Pollutants,Pollutant, Air,Pollutants, Air,Pollutants, Air Environmental,Pollutants, Environmental Air
D000485 Allergens Antigen-type substances that produce immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE). Allergen
D001249 Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). Asthma, Bronchial,Bronchial Asthma,Asthmas
D012905 Smog A mixture of smoke and fog polluting the atmosphere. (Dorland, 27th ed)

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