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A simple method of irradiating cells in vitro with beta particles is to add the beta-emitter to a cell suspension; various dosimetric aspects of this procedure have been investigated. It is shown that, due to the different water content of the various constituents of a blood cell suspension, the average dose D beta absorbed by a certain type of cells for a tritium nominal concentration Co and an irradiation time t is given by D beta(t) = KEnCo eta t. Typical values of the factor eta are calculated for lymphocytes. A series of experiments has demonstrated that whilst the uptake phase has negligible effect on the dose, a significant error may arise during washing-out because a proportion of the activity remains in the cells.
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N Vulpis, and
M E De Santis, and
G Vulpis
July 1987,
Health physics,
G Scarpa, and
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G Vulpis
June 2001,
Health physics,
G Scarpa, and
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G Vulpis
December 1987,
Physics in medicine and biology,
G Scarpa, and
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January 1978,
Current topics in radiation research quarterly,
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December 1988,
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March 1984,
Radiation research,
G Scarpa, and
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May 1963,
The British journal of radiology,
G Scarpa, and
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January 1980,
Medical physics,
G Scarpa, and
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G Vulpis
January 1994,
Toxicology letters,
G Scarpa, and
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October 1963,
Radiation research,
