-transparent.png){kind=logo}
Quantitative ultrastructural studies of human gastric mucosal chief cells during secretory stimulation have not been reported previously. In five healthy subjects we studied the effect of intravenous administration of 2 CU/kg of GIH secretin on gastric chief-cell ultrastructure. Gastric biopsies for quantitative ultrastructural analysis were obtained before and 15 and 30 min after secretin administration. Electron micrographs of 150 chief cells were analyzed by the Loud quantitative method. After secretin administration the percentage area occupied by zymogen granules decreased significantly at 15 and 30 min. At corresponding times membrane profile concentration (rough endoplasmic reticulum) increased significantly over basal values. This study provides morphological evidence of increased activity of chief cells after secretin administration.
J Stachura, and
K J Ivey, and
A Tarnawski, and
W J Krause, and
P Stogsdill
January 1978,
Gastroenterologia Japonica,
J Stachura, and
K J Ivey, and
A Tarnawski, and
W J Krause, and
P Stogsdill
January 1989,
Histochemistry,
J Stachura, and
K J Ivey, and
A Tarnawski, and
W J Krause, and
P Stogsdill
July 1970,
Naika hokan. Japanese archives of internal medicine,
J Stachura, and
K J Ivey, and
A Tarnawski, and
W J Krause, and
P Stogsdill
January 1990,
Journal of clinical gastroenterology,
J Stachura, and
K J Ivey, and
A Tarnawski, and
W J Krause, and
P Stogsdill
June 2002,
TheScientificWorldJournal,
J Stachura, and
K J Ivey, and
A Tarnawski, and
W J Krause, and
P Stogsdill
February 1970,
The British journal of surgery,
J Stachura, and
K J Ivey, and
A Tarnawski, and
W J Krause, and
P Stogsdill
September 1964,
Gastroenterology,
J Stachura, and
K J Ivey, and
A Tarnawski, and
W J Krause, and
P Stogsdill
August 1985,
Klinicheskaia meditsina,
J Stachura, and
K J Ivey, and
A Tarnawski, and
W J Krause, and
P Stogsdill
April 1974,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
J Stachura, and
K J Ivey, and
A Tarnawski, and
W J Krause, and
P Stogsdill
March 2003,
Regulatory peptides,
