Biomaterial Database

Subcortical connections of the prefrontal cortex in dogs: afferents to the medial cortex. 1981

A Kosmal

Afferent subcortical connections to the medial prefrontal cortex (PFC) in the dog were investigated using the horseradish peroxidase retrograde transport method. The dorsal and ventral regions of the medial PFC receive different projections both from the mediodorsal and the ventral thalamic nuclei. The dorsomedial PFC receives projection from a dorsolateral region of the "parvocellular" MD subdivision, while the ventromedial PFC - from the medial, "magnocellular" MD subdivision. The area precruciata medialis (XM) is involved in significant MD projection and should be included in the "prefrontal" not the "premotor" cortex. The ventral thalamic nuclei project mainly to the dorsomedial but not the ventromedial cortex. The distribution of this projection was correlated with antero-posterior cortical localization of injections. The main criterion for distinguishing "prefrontal" and "motor" cortex remains its projections either from MD or from VL nuclei. Only the ventromedial prefrontal cortex receives projection from anterior thalamic nuclei. The caudal region of the ventromedial prefrontal cortex seems to receive richer projection from "non-specific" thalamic nuclei as well as from the amygdaloid complex.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D005260	Female		Females
D005625	Frontal Lobe	The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.	Brodmann Area 8,Brodmann's Area 8,Frontal Cortex,Frontal Eye Fields,Lobus Frontalis,Supplementary Eye Field,Area 8, Brodmann,Area 8, Brodmann's,Brodmanns Area 8,Cortex, Frontal,Eye Field, Frontal,Eye Field, Supplementary,Eye Fields, Frontal,Frontal Cortices,Frontal Eye Field,Frontal Lobes,Lobe, Frontal,Supplementary Eye Fields
D006735	Horseradish Peroxidase	An enzyme isolated from horseradish which is able to act as an antigen. It is frequently used as a histochemical tracer for light and electron microscopy. Its antigenicity has permitted its use as a combined antigen and marker in experimental immunology.	Alpha-Peroxidase,Ferrihorseradish Peroxidase,Horseradish Peroxidase II,Horseradish Peroxidase III,Alpha Peroxidase,II, Horseradish Peroxidase,III, Horseradish Peroxidase,Peroxidase II, Horseradish,Peroxidase III, Horseradish,Peroxidase, Ferrihorseradish,Peroxidase, Horseradish
D000344	Afferent Pathways	Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.	Afferent Pathway,Pathway, Afferent,Pathways, Afferent
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013787	Thalamic Nuclei	Several groups of nuclei in the thalamus that serve as the major relay centers for sensory impulses in the brain.	Nuclei, Thalamic