The dermal-epidermal junction during the development of skin and cutaneous appendages in the chick embryo. 1981

M Demarchez, and A Mauger, and P Sengel

The ultrastructure of the junction zone between dermis and epidermis was examined in the chick embryo during the development of feather-forming, scale-forming and glabrous skin. Direct contacts between dermal and epidermal cells were extremely rare and seen sporadically in feather-forming skin only, in connection with anchor filaments. Everywhere else, the basement membrane (BM) comprised an uninterrupted lamina densa. In feather-forming skin, zones of close parallel apposition (CPA) of dermal cell processes against the BM lamina densa were frequent at the margin of feather buds and at the base of feather filaments, and scarce in interplumar skin. In scale-forming skin, the density of CPA was lower, at 10 days, in the interplacode region than within the scale primordium, and, at 11 and 12 days, at the apex of the scale than at its base. At 11 days, dermal cells in scale primordia were equipped with long and thin tubular processes oriented predominantly at right angle with respect to the basal-apical axis of the scale. In the midventral apterium, CPA of dermal cell processes against the BM was very rare at 12 days, and non-existent at later stages, when a complex collagenous matrix was laid down in orthogonal ply-wood fashion underneath the BM lamina densa. Thus, it appeared that the heterogeneity of the distribution of dermal cell processes beneath the basement membrane might represent part of the morphogenetic message that the dermis is known to transmit to the epidermis during the formation of the appendages.

UI MeSH Term Description Entries
D008854 Microscopy, Electron Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen. Electron Microscopy
D002642 Chick Embryo The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching. Embryo, Chick,Chick Embryos,Embryos, Chick
D004817 Epidermis The external, nonvascular layer of the skin. It is made up, from within outward, of five layers of EPITHELIUM: (1) basal layer (stratum basale epidermidis); (2) spinous layer (stratum spinosum epidermidis); (3) granular layer (stratum granulosum epidermidis); (4) clear layer (stratum lucidum epidermidis); and (5) horny layer (stratum corneum epidermidis).
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012867 Skin The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

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