[Utilization of minicomputer for the quality control of radioimmunoassay (author's transl)]. 1981

K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai

In our nuclear medicine laboratory the quality control (QC) of radioimmunoassay (RIA) has been performed along the line of WHO program for standardization and quality control of RIA. The QC procedure was automated using a minicomputer in order to avoid tedious and time-consuming hand processing. The program was written with BASIC language. The counts of radioactivity measured in autowell counters are regarded in PTR, through which the data are read into a minicomputer (Scintipac 200). After informations on the concentrations of standards are registered through keyboard of CRT, the data processing is performed including curve fitting, dose calculation and quality control. As the indicators for QC response error relationship (RER), standard curve, precision profile and QC chart are displayed on CRT. On the basis of rejection criteria using these indicators, bad assays are identified to be omitted from reporting. The subroutine installed in the minicomputer system is used for the storage of data on QC samples in each assay, which are used for construction of QC charts. The use of a minicomputer enables implementation of QC of RIA on routine basis with ease and speed.

UI MeSH Term Description Entries
D008905 Minicomputers Small computers that lack the speed, memory capacity, and instructional capability of the full-size computer but usually retain its programmable flexibility. They are larger, faster, and more flexible, powerful, and expensive than microcomputers. Minicomputer
D011786 Quality Control A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed) Control, Quality,Controls, Quality,Quality Controls
D011863 Radioimmunoassay Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation. Radioimmunoassays
D003201 Computers Programmable electronic devices designed to accept data, perform prescribed mathematical and logical operations at high speed, and display the results of these operations. Calculators, Programmable,Computer Hardware,Computers, Digital,Hardware, Computer,Calculator, Programmable,Computer,Computer, Digital,Digital Computer,Digital Computers,Programmable Calculator,Programmable Calculators
D013974 Thyroxine The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. L-Thyroxine,Levothyroxine,T4 Thyroid Hormone,3,5,3',5'-Tetraiodothyronine,Berlthyrox,Dexnon,Eferox,Eltroxin,Eltroxine,Euthyrox,Eutirox,L-3,5,3',5'-Tetraiodothyronine,L-Thyrox,L-Thyroxin Henning,L-Thyroxin beta,L-Thyroxine Roche,Levo-T,Levothroid,Levothyroid,Levothyroxin Deladande,Levothyroxin Delalande,Levothyroxine Sodium,Levoxine,Levoxyl,Lévothyrox,Novothyral,Novothyrox,O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine,O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine,Oroxine,Sodium Levothyroxine,Synthroid,Synthrox,Thevier,Thyrax,Thyroxin,Tiroidine,Tiroxina Leo,Unithroid,L Thyrox,L Thyroxin Henning,L Thyroxin beta,L Thyroxine,L Thyroxine Roche,Levo T,Thyroid Hormone, T4

Related Publications

K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai
April 1980, Rinsho byori. The Japanese journal of clinical pathology,
K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai
November 1978, Wiener klinische Wochenschrift,
K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai
August 1977, Radioisotopes,
K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai
November 1979, La Nouvelle presse medicale,
K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai
March 1977, Nihon Naibunpi Gakkai zasshi,
K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai
January 1981, Sangre,
K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai
April 1978, Iyo denshi to seitai kogaku. Japanese journal of medical electronics and biological engineering,
K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai
November 1980, Horumon to rinsho. Clinical endocrinology,
K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai
September 1980, Horumon to rinsho. Clinical endocrinology,
K Tabushi, and A Harada, and Y Sasaki, and S Itoh, and Y Watanabe, and K Mishio, and T Nakajima, and S Matsukawa, and M Sakura, and T Ishihara, and T Nagai
April 1980, Kaku igaku. The Japanese journal of nuclear medicine,
Copied contents to your clipboard!