Biomaterial Database

Gross pathology of the placenta in intrauterine growth retardation. 1981

K Bjøro

A prospective study of placental pathology in intrauterine growth retardation (IUGR) has been performed with a total of 223 placentas during a ten-year period. The material is divided into subgroups with or without hypertensive complications of pregnancy. Velamentous insertion, single umbilical artery (SUA) and placental infarct occurred more frequently in the IUGR group than in a reference material comprising 500 normal deliveries. Such a prevalence was not observed with marginal insertion, circumvallate placenta or true knot formation. Velamentous insertion and SUA, probably compromising the foetal blood circulation to some extent, occurred more frequently in the normotensive group than in the hypertensive group. Seven out of 11 cases with SUA were associated with foetal malformations. Anomalies in the placenta and in the umbilical cord affecting the foetal blood circulation are simple to recognize by naked-eye examination. Our prospective study of placentas in a series of IUGR cases shows that a routinely performed examination of the placenta in the delivery department may help to clarify the pathogenesis of retarded foetal growth in normotensive pregnancy.

UI	MeSH Term	Description	Entries
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007236	Infant, Small for Gestational Age	An infant having a birth weight lower than expected for its gestational age.
D007238	Infarction	Formation of an infarct, which is NECROSIS in tissue due to local ISCHEMIA resulting from obstruction of BLOOD CIRCULATION, most commonly by a THROMBUS or EMBOLUS.	Infarct,Infarctions,Infarcts
D010920	Placenta	A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES).	Placentoma, Normal,Placentome,Placentas,Placentomes
D010922	Placenta Diseases	Pathological processes or abnormal functions of the PLACENTA.	Placenta Disorders,Placental Diseases,Disease, Placenta,Disease, Placental,Diseases, Placenta,Diseases, Placental,Disorder, Placenta,Disorders, Placenta,Placenta Disease,Placenta Disorder,Placental Disease
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D005260	Female		Females
D005317	Fetal Growth Retardation	Failure of a FETUS to attain expected GROWTH.	Growth Retardation, Intrauterine,Intrauterine Growth Retardation,Fetal Growth Restriction,Intrauterine Growth Restriction
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man