Biomaterial Database

[The use of megestrol acetate to stop urine spraying in castrated male cats (author's transl)]. 1981

A Chalifoux, and Y Gosselin

The use of megestrol acetate to stop urine spraying in castrated male cats Four castrated male cats were treated with megestrol acetate because they were showing signs of urine spraying. The dosage used was 5 mg a day for seven days followed by 5 mg every three days for 21 days. The treatment did not exceed one month. Treatment was successful in three of the four animals with this therapeutic regime. A relapse was noticed one year after the initial treatment in two of these cats. Treatment was resumed in one case, while in the other case spontaneous regression of urine spraying occurred. No relapse have been reported after six months. Other methods of treatment used to suppress this undesirable behavior are also discussed.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008535	Megestrol	A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.	17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione,Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-
D002369	Castration	Surgical removal or artificial destruction of gonads.	Gonadectomy,Castrations,Gonadectomies
D002415	Cats	The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)	Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D004609	Eliminative Behavior, Animal	Behavior associated with the elimination of feces and urine from the body.	Eliminative Behavior,Animal Eliminative Behavior,Animal Eliminative Behaviors,Behavior, Animal Eliminative,Behavior, Eliminative,Behaviors, Animal Eliminative,Behaviors, Eliminative,Eliminative Behaviors,Eliminative Behaviors, Animal
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001522	Behavior, Animal	The observable response an animal makes to any situation.	Autotomy Animal,Animal Behavior,Animal Behaviors
D014554	Urination	Discharge of URINE, liquid waste processed by the KIDNEY, from the body.	Micturition