[Detection of antitetanic antibodies. Technics (electrosyneresis, Laurell, latex) applied to a high-antibody population]. 1978

J Hainaut, and P Fenieres, and A Goldcher, and P Guenver, and G Avenard

The human serum of about twenty years old men, recently vaccinated has been tested by Laurell's method (Mesnier and Piquet variant). Purified antitetanic equine serum from Pasteur Institute (P.I.) has been taken as reference. With 5 Lf tetanic toxoid from P.I. concentration we can trust in the results until 50 antitetanics I.U. For richer serum, a 10 Lf toxoid concentration must be used. Correspondance between Pasteur Institute serum and gamma TS (human specific immunoglobulins) is indicated. Technics of Laurell, latex and electroimmunodiffusion are compared. The way to obtain plasma pool with higher antitetanic titre than 8 I.U. from poor and rich plasma is mentionned. The highest rate of titre antibody after the first typhoid diphteria tetanic vaccinal injection is observed between the 11th and 21th day.

UI MeSH Term Description Entries
D007841 Latex Fixation Tests Passive agglutination tests in which antigen is adsorbed onto latex particles which then clump in the presence of antibody specific for the adsorbed antigen. (From Stedman, 26th ed) Latex Agglutination Tests,Agglutination Test, Latex,Agglutination Tests, Latex,Fixation Test, Latex,Fixation Tests, Latex,Latex Agglutination Test,Latex Fixation Test,Test, Latex Agglutination,Test, Latex Fixation,Tests, Latex Agglutination,Tests, Latex Fixation
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D003378 Counterimmunoelectrophoresis Immunoelectrophoresis in which immunoprecipitation occurs when antigen at the cathode is caused to migrate in an electric field through a suitable medium of diffusion against a stream of antibody migrating from the anode as a result of endosmotic flow. Electrosyneresis,Immunoelectroosmophoresis,Immunoelectrophoresis, Countercurrent,Immunoelectrophoresis, Crossover,Countercurrent Immunoelectrophoresis,Crossover Immunoelectrophoresis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013743 Tetanus Antitoxin An antitoxin used for the treatment of TETANUS. Antitoxin, Tetanus

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