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The feasibility of patient determination of fast fraction hemoglobin (HbA1) was evaluated. In the laboratory, the fast fraction method correlated well with known mixed standards of between 0 and 40% hemoglobin A1c (r2 = 0.97, slope 1.19) and reasonably well with radioimmunoassay (r2 = 0.78, slope 1.09), although prepackaged columns performed poorly about 18% of the time. Sixteen patients practicing home blood monitoring performed the determination of HbA1 on their own blood obtained from fingerstick. Two hours of patient training were required for the procedure. The correlation of patient determination of HbA1 with the results obtained by the laboratory on venous blood was reasonable (r2 = 0.81 with a slope of 0.88). Patient performance of HbA1 was useful in (1) providing enhanced reinforcement for self-monitoring programs, (2) engaging patients in groups in the monitoring process, and (3) providing an educational tool with which to teach pathophysiologic principles involved in diabetes mellitus.
K McDermott, and
M Cooks, and
C M Peterson
March 1982,
JAMA,
K McDermott, and
M Cooks, and
C M Peterson
March 1983,
Clinical chemistry,
K McDermott, and
M Cooks, and
C M Peterson
January 1984,
Critical reviews in clinical laboratory sciences,
K McDermott, and
M Cooks, and
C M Peterson
August 1976,
Drug intelligence & clinical pharmacy,
K McDermott, and
M Cooks, and
C M Peterson
January 1986,
Panminerva medica,
K McDermott, and
M Cooks, and
C M Peterson
October 1981,
JAMA,
K McDermott, and
M Cooks, and
C M Peterson
November 1968,
Journal of medical education,
K McDermott, and
M Cooks, and
C M Peterson
April 1946,
The Journal of psychology,
K McDermott, and
M Cooks, and
C M Peterson
July 1979,
American pharmacy,
K McDermott, and
M Cooks, and
C M Peterson
January 1988,
The Diabetes educator,
