Changes in bone histomorphometry and bone mineral during treatment of osteoporosis with 1 alpha-hydroxyvitamin D3 and calcium. 1981

T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle

Treatment with 1 alpha-OHD3 supplemented with calcium will possibly unveil symptoms of spinal pain (8/10) and increase physical activity (7/10) in patients suffering from osteoporosis. An increase in trabecular bone (8/10) as well as a decrease in bone resorption (9/10) accompanied by measured increased bone mineral (6/10) has been observed. Some patients did not show any response to this kind of treatment.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D008903 Minerals Native, inorganic or fossilized organic substances having a definite chemical composition and formed by inorganic reactions. They may occur as individual crystals or may be disseminated in some other mineral or rock. (Grant & Hackh's Chemical Dictionary, 5th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Mineral
D010018 Osteomalacia Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis. Adult Rickets,Rickets, Adult
D010024 Osteoporosis Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. Age-Related Osteoporosis,Bone Loss, Age-Related,Osteoporosis, Age-Related,Osteoporosis, Post-Traumatic,Osteoporosis, Senile,Senile Osteoporosis,Osteoporosis, Involutional,Age Related Osteoporosis,Age-Related Bone Loss,Age-Related Bone Losses,Age-Related Osteoporoses,Bone Loss, Age Related,Bone Losses, Age-Related,Osteoporoses,Osteoporoses, Age-Related,Osteoporoses, Senile,Osteoporosis, Age Related,Osteoporosis, Post Traumatic,Post-Traumatic Osteoporoses,Post-Traumatic Osteoporosis,Senile Osteoporoses
D001842 Bone and Bones A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX. Bone Tissue,Bone and Bone,Bone,Bones,Bones and Bone,Bones and Bone Tissue,Bony Apophyses,Bony Apophysis,Condyle,Apophyses, Bony,Apophysis, Bony,Bone Tissues,Condyles,Tissue, Bone,Tissues, Bone
D002112 Calcifediol The major circulating metabolite of VITAMIN D3. It is produced in the LIVER and is the best indicator of the body's vitamin D stores. It is effective in the treatment of RICKETS and OSTEOMALACIA, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties. 25-Hydroxycholecalciferol,25-Hydroxyvitamin D 3,25-Hydroxycholecalciferol Monohydrate,25-Hydroxyvitamin D3,Calcidiol,Calcifediol Anhydrous,Calcifediol, (3 alpha,5Z,7E)-Isomer,Calcifediol, (3 beta,5E,7E)-Isomer,Calderol,Dedrogyl,Hidroferol,25 Hydroxycholecalciferol,25 Hydroxycholecalciferol Monohydrate,25 Hydroxyvitamin D 3,25 Hydroxyvitamin D3,Anhydrous, Calcifediol,Monohydrate, 25-Hydroxycholecalciferol
D002118 Calcium A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Coagulation Factor IV,Factor IV,Blood Coagulation Factor IV,Calcium-40,Calcium 40,Factor IV, Coagulation
D004359 Drug Therapy, Combination Therapy with two or more separate preparations given for a combined effect. Combination Chemotherapy,Polychemotherapy,Chemotherapy, Combination,Combination Drug Therapy,Drug Polytherapy,Therapy, Combination Drug,Chemotherapies, Combination,Combination Chemotherapies,Combination Drug Therapies,Drug Polytherapies,Drug Therapies, Combination,Polychemotherapies,Polytherapies, Drug,Polytherapy, Drug,Therapies, Combination Drug
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle
January 1982, Scandinavian journal of rheumatology,
T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle
June 1984, Italian journal of orthopaedics and traumatology,
T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle
May 1994, Calcified tissue international,
T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle
August 1988, Nihon Seikeigeka Gakkai zasshi,
T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle
March 1993, Bone and mineral,
T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle
February 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,
T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle
June 1990, Zhonghua nei ke za zhi,
T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle
January 1980, Contributions to nephrology,
T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle
November 1988, Polski tygodnik lekarski (Warsaw, Poland : 1960),
T S Lindholm, and O S Nilsson, and E Elmstedt, and S A Eriksson, and T C Lindholm, and B R Kyhle
September 1978, Clinical orthopaedics and related research,
Copied contents to your clipboard!