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Clinical and laboratory investigations were performed to test the criteria used in infusion tomography of the gallbladder (ITGB) for the diagnosis of acute cholecystitis. The results demonstrated a 14% incidence of gallbladder wall visualization in 200 patients asymptomatic for gallbladder disease undergoing excretory urography with tomography. The animal investigation showed no significant difference (0.1 less than p less than 0.2) in radiographic results between control (n = 6) and acute cholecystitis (n = 7) groups. Serious questions are raised regarding the clinical reliability of ITGB using currently accepted diagnostic criteria.
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